Published:
January 16, 2026
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Last Updated:
January 16, 2026

What Is Suboxone? How It Works for Opioid Addiction

Key Takeaways

  • Suboxone is an FDA-approved medication used to treat opioid use disorder.
  • It can reduce withdrawal symptoms and cravings without the same high that other opioids cause.
  • Treatment is flexible and convenient, allowing people to adjust over time.
  • Restarts and long-term care are expected, and using medication is a highly effective way to manage opioid use.

Suboxone is a prescription medication used to treat opioid use disorder. It combines buprenorphine, which partially activates opioid receptors to reduce cravings and withdrawal, and naloxone, which helps prevent misuse.

Growing up with a parent who struggled with drug and alcohol use, I saw firsthand just how unclear and complicated the path to recovery could often be. Thankfully, medications like Suboxone have made it easier for many people to reduce their opioid use and start feeling more in control of their lives. 

While highly effective, there's still some confusion around how Suboxone works, and misunderstandings about opioid medicines can have real consequences. Even though Suboxone and other drugs work well, research shows that only 25% of people in the U.S. get medication to treat opioid use. This is why the availability of high-quality information, and accessible resources is so essential.

Getting treatment can be hard for many reasons. Appointments can be tough to schedule, clinics may be far away, insurance can be confusing, and some medications have extra rules that make them harder to get. Boulder helps fix this by making proven treatments more accessible while removing unnecessary obstacles.

If you have questions about Suboxone, this article will make things clearer. We'll walk through how this medication works and why it's used to treat opioid use disorder. We'll also talk about what treatment can realistically look like, including the ups, downs, and flexibility that's built into long-term care.

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What is Suboxone?

Suboxone is a prescription medication used to treat opioid use disorder. It is usually taken once a day as a dissolvable film or tablet placed under the tongue or inside the cheek. Its generic name, buprenorphine/naloxone, refers to the two medicines it contains, each of which serves a specific purpose:

  • Buprenorphine is the main therapeutic ingredient that helps reduce cravings, risk of overdose, and eases withdrawal.
  • Naloxone is included as a built-in safety feature to ensure the medication is used as intended.

Buprenorphine is available in several formulations, including the dissolvable Suboxone and Zubsolv, as well as the long-acting injections Sublocade and Brixadi. Most formulations combine buprenorphine with naloxone, which is included to discourage misuse by injection.

Opioids affect receptors throughout the brain and body, particularly those involved with mood, pain, and breathing. Most opioids become more dangerous when taken in larger amounts, which is why overdose can happen. 

Buprenorphine works differently. It binds tightly to the opioid receptors but doesn’t activate them all the way. That helps ease withdrawal and cravings without the intense rush or sedation caused by other opioids.

Suboxone is a medicine that helps people who are recovering from opioids. It stops the painful parts of quitting, reduces your risk of overdose, and calms your cravings. “Buprenorphine creates stability so people can get back to their lives. When someone isn’t constantly battling withdrawal or cravings, they can focus on what matters–their families, their work, their goals,” says addiction medicine physician Dr. Ayesha Appa.

Boulder's treatment focuses on making someone's situation safer and more stable right now. The aim is to lower risk, improve quality of life, and make it easier to move toward recovery goals. That happens best when it fits into real life.

What is Suboxone used for?

Suboxone is used to help people manage their opioid use, whether they want to reduce it or stop altogether. It is approved by the U.S. Food and Drug Administration (FDA) for this purpose. While Suboxone is not a one-time cure, it serves as a powerful partner in your recovery. By providing relief from withdrawal and calming cravings, it helps you stay safe and creates stability as you move forward in your journey.

“Buprenorphine is one of the most effective medications we have in all of medicine. Study after study shows it helps people with opioid use disorder live longer, healthier lives,” Dr. Appa says.

Because it works more gently on the brain than drugs like heroin, fentanyl, or prescription painkillers, it can help stop the cycle of feeling sick, using opioids, and then crashing again. For many people, this makes it easier to avoid overdose and get back to daily life, including focusing on work, relationships, and health.

When Suboxone Isn't the Right Choice

Suboxone may not be recommended in some situations, including when:

  • You're not using opioids regularly, since this medication is meant for people who are dependent on opioids.
  • You’re allergic to buprenorphine, naloxone, or other ingredients in Suboxone.
  • You have certain medical conditions, such as severe liver problems, that make this medication unsafe for you.
  • You’re taking medications that could lead to dangerous interactions without close medical supervision, such as benzodiazepines or certain antibiotics.

Your Boulder Care provider will partner with you to determine if Suboxone is the best path forward, or if a different approach feels more like the right fit for your life. Beyond daily medication, we also offer long-acting options like Sublocade and Brixadi in most states, ensuring you have a choice in how you manage your recovery.

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How does Suboxone work?

Suboxone works by changing how opioids affect the brain and body. Understanding how it works can help family members and other support people feel more confident about why it’s used.

It’s also helpful to know exactly what's in Suboxone. It contains two medicines that work together:

  • Buprenorphine attaches to the same brain receptors as opioids like heroin, fentanyl, or pain pills, but it acts more gently. It helps ease withdrawal and cravings without creating the intense rush or sedation caused by other opioids. Because of the way it works, there is a limit, or ceiling effect, to how strong its effects can be, which helps reduce the risk of overdose.
  • Naloxone is a built-in safety feature to ensure the medication works exactly as intended. When taken as directed (dissolved under the tongue), the Naloxone stays inactive and doesn’t interfere with your treatment. However, it is designed only to become active if the medication is injected, which helps protect you by preventing the drug from being used in an unsafe way.

If Suboxone is taken improperly, it can cause unpleasant or potentially dangerous effects. These can include sudden withdrawal symptoms, breathing problems, or other serious side effects, especially if it is mixed with alcohol or sedatives like benzodiazepines.

When taken as prescribed, Suboxone is a safe and reliable tool that balances brain chemistry and provides the stability needed for lasting recovery.

"One thing I hear from patients is that buprenorphine helps the world feel clearer. Instead of feeling sedated, they feel a bit more alert and present. For some, that clarity is exactly what they need. For others, it takes getting used to," Dr. Appa explains.

Suboxone is taken by placing a film or tablet under the tongue (or sometimes inside the cheek), where it slowly dissolves. This allows the medication to absorb properly and work to reduce cravings and withdrawal symptoms throughout the day. Other forms of buprenorphine, such as Sublocade and Brixadi, are available as extended-release injections.

The benefits of Suboxone treatment

When Suboxone is working, people often notice several positive changes. Research shows that using Suboxone for opioid use disorder can reduce cravings, withdrawal, and the risk of overdose, particularly when treatment is used for a year or longer. 

Reduced risk of overdose 

When people use Suboxone as a medication for opioid use disorder (MOUD), it makes overdoses and serious health problems less likely. Research has found that people taking buprenorphine or methadone had about a 76% lower risk of overdose at 3 months, and a 59% lower risk at 12 months compared to people who were not receiving MOUD. 

Another study found that every 100 days of treatment with buprenorphine was linked to a 36% lower risk of opioid overdose compared to not receiving any medication.

Better treatment retention and stability

People who stay in treatment longer tend to have better outcomes. Suboxone can help with that. In one study, each additional month of treatment was associated with about a 25% lower risk of using nonprescribed opioids. Evidence shows that people who take buprenorphine are more likely to stay in treatment compared to those who don’t receive medication.

Lower risk of hospitalization

People who continue taking buprenorphine for over a year are less likely to experience hospitalizations and emergency room visits compared to those who stop taking medication earlier.

Reduced opioid use and cravings

Suboxone helps people use fewer opioids by lowering cravings and making withdrawal easier. This makes it much less likely that people will go back to using opioids.

In one study, people taking Suboxone were less likely to test positive for opioids. They also had more days in a row without using drugs and fewer cravings. This shows that taking Suboxone can help people use fewer opioids.

Supports stability and recovery goals

Everyone is different, but most people say these medicines help them feel much better. When you aren’t fighting cravings, it is easier to do the things you love, like:

  • Taking care of your home and family
  • Doing a good job at work or school
  • Build better relationships with friends and family
  • Joining in and enjoying life again

A survey of treatment providers found that reduced cravings and illicit drug use were the most often cited benefits of buprenorphine and other opioid medications.

Other benefits

Suboxone can also help people who are dependent on kratom. Kratom is an herbal product—that comes from the leaves of the Mitragyna speciosa tree—that works on the same receptors as opioids, and people may feel sick when they try to stop taking it. 

Some research has shown that buprenorphine and naloxone (the medications in Suboxone) can help people stop using kratom. This is an off-label use, but it shows that Suboxone can sometimes help people regain control when kratom use feels hard to manage. 

Myths and misconceptions about Suboxone

There's a lot of mixed messaging around Suboxone and opioid treatment in general. A lot of that comes from outdated beliefs about recovery that don't always line up with real life. Before getting into the details of treatment, it helps to clear up a few common myths that often cause confusion.

Myth: “Suboxone is just replacing one drug with another.”

Suboxone is also an opioid, so there’s a common misconception that taking it is just replacing one thing for another. But taking prescribed medication is not the same as uncontrolled opioid use. 

"That idea comes from stigma, not science,” explains Patricia Pechter, MD, DABFM, a clinical quality improvement physician at Boulder Care. “Suboxone isn’t a substitute for getting high; it’s a treatment for a medical condition. Like insulin for diabetes or inhalers for asthma, it’s an FDA-approved medication that helps stabilize the brain and reduce cravings so people can rebuild their lives.”

Studies actually show that people who take Suboxone are more stable and less likely to experience an overdose, which is a primary goal of treatment.

Myth: “If someone is dependent on Suboxone, then they’re addicted to it.”

While people often use the words addiction and dependence to describe drug use, they don’t mean the same thing. 

  • Physical dependence means a person’s body is used to a medication. This can happen with many types of medicine, including blood pressure medicine and antidepressants. Being dependent on them doesn’t mean that a person is addicted to them.
  • Addiction involves a loss of control and using the substance in harmful ways. When a person is addicted, they also keep using a substance even after experiencing negative consequences because of it.

While the body can become physically dependent on Suboxone–much like it does with medicine for blood pressure or diabetes–it’s important to remember that this is very different from the cycle of addiction. Instead of losing control, Suboxone actually helps you regain control. It provides the physical stability your body needs to function well, stay healthy, and live safely.

Myth: “People should be able to quit without medication.”

Some people believe that willpower or behavioral treatments should be enough to quit using drugs. While willpower is an important part of any journey, it’s often not enough on its own to overcome the physical changes opioids cause in the brain.

Opioid use disorder is a chronic brain condition, not a choice. Suboxone helps to heal some of those changes, providing a foundation that allows the behavioral treatments and your own determination to truly succeed.

Using medicine to help you get better is not ‘cheating’ and it does not make you weak. It is a smart, medical choice that works. Just like someone with asthma uses an inhaler to breathe, you are using a tool to stay healthy. This medicine helps you stick to your goals and keeps you safe.

Myth: “Once you start Suboxone, you’ll be taking it forever.”

There’s no “right” timeline for recovery. Some people stay on Suboxone for months, while others continue using it for years. Research has shown that longer use is linked to better safety outcomes. There is no set timeline for stopping medication. It’s a decision people make with their doctor based on what feels right for their situation.

“Suboxone helps people move toward health, stability, and recovery. Many stay on it for years and do very well. Others taper off when they’re ready if that’s their goal. Either way, it’s a tool that works,” Dr. Pechter says.

Myth: “Suboxone is only for people with serious drug use.”

Suboxone can help anyone who uses opioids more than they’d like to or feels that they want to get out of a cycle of use that they can’t control. Early support can be helpful. 

One study found that people who started buprenorphine-naloxone treatment within 30 days of their opioid use disorder diagnosis had much better results than people who started later. Early treatment was associated with a 42% lower risk for opioid overdose and a 51% lower risk of ER visits in the first year after diagnosis.

Myth: “Subxone isn’t for people who use fentanyl.”

Research has found that people taking buprenorphine and naloxone were much less likely to show fentanyl in drug tests than those who were not in treatment. Even if you have used opioids, including fentanyl, for a long time or in large amounts, this medicine can still work for you. You may need to start the medication slowly, very quickly, or even need a higher dose of Suboxone.

What does Suboxone treatment look like?

Boulder offers same-day virtual care with no judgment, something that Dr. Pechter says is surprisingly rare in addiction treatment. The process is simple, and it takes place entirely on your phone. It means no sitting in waiting rooms or driving across town. You can talk to your doctor at home or wherever you feel safest.

“You download the app, complete onboarding, and meet with a clinician to create a plan that fits your goals. We consistently get feedback from patients that if they knew how straightforward it would be to get into Boulder Care, they would have tried it a long time ago,” Dr. Pechter says.

Here's what your journey might look like:

Step 1: Getting Started

The first step is called "induction." It's the initial stage of treatment where someone transitions from taking opioids to taking Suboxone. This process helps get your body used to Suboxone in a way that minimizes withdrawal symptoms and sets you up for long-term success.

  • Enroll through the app: You'll enroll through the app and complete a quick eligibility check. Once you're approved, you'll enter a virtual queue to wait for your first visit right on your phone.
  • Talk to a Medical Assistant: You'll have an initial visit with a Care Advocate who will talk to you about your history, answer your questions, and help set up your pharmacy.
  • Get a prescription from a clinician: Next, you'll connect with a clinician who will complete a medical visit and prescribe that is appropriate for your situation.

Treatment induction will be individualized for your needs. Some people follow a standard start schedule, while others opt to explore newer options like Boulder's QuickStart method, which makes the transition faster and more predictable.

You may feel unsettled and uncomfortable before Suboxone has time to fully kick in. Remember, Medical Assistants and clinicians are there to help, adjust dosing, and offer supportive meds if needed.

“We support people through the transition onto Suboxone, including prescribing medications to ease withdrawal and helping them control the pace of starting treatment,” Dr. Pechter explains. “That flexibility makes a big difference, especially for people who struggled with Suboxone in the past.”

Step 2: Stabilization

The stabilization phase involves finding what works best for you. You'll work with your clinician to fine-tune your dose and schedule so that you can start to feel life returning to normal.

  • Regular check-ins: You’ll have regular check-ins to see how you're feeling and adjust your medication as needed.
  • Identifying what works: You'll learn more about what dosing feels best for you, how to handle triggers or cravings, and how to balance Suboxone with your daily routine.
  • Flexible support: You can message your team, access education, find encouragement, and join video visits through the app whenever you need it, not just during scheduled appointments. “Many patients also work with a Peer Recovery Specialist: someone who’s been there and understands recovery from the inside. Support looks different for everyone, and we make space for that,” Dr. Pechter says.

Step 3. Maintenance

Once your body is responding well to Suboxone and the cravings are reduced, you enter the maintenance phase, where your medication helps support your daily routines.

  • Fewer cravings: People taking Suboxone typically feel fewer cravings and spend less time thinking about opioids. That means you’ll be better able to focus on your family, work, rest, and hobbies instead of worrying about withdrawal symptoms and searching for opioids.
  • Convenience: Virtual on-demand visits through the Boulder app let you renew your prescriptions, check in with a clinician, and connect with support staff when it works for you.
  • Support: You can also work with case managers and peer recovery specialists to deal with challenges, build supportive routines, and find additional resources in your community.
  • Flexibility: Life gets busy, challenges happen, and sometimes you may need to adjust your goals. If you need to pause or restart treatment, your Boulder team can help you navigate those challenges without judgment.

Step 4: Long-Term Support

Recovery isn't a one-and-done process. Each person’s experience is different. Some people take Suboxone for months, others for years. Staying connected with support, even as you gradually need less intensive care, can reduce risk and improve stability.

  • Connected care: Boulder's telehealth approach means that support is always there right in your phone. You can check in, message your team, and book appointments any time you need to, all without leaving your home.
  • Pauses and restarts happen: Whether you need to restart medications after a stressful event or want to change your goals, your treatment team will be there to walk you through the next steps with respect and empathy.

Recovery takes time. There will be good days, hard days, and everything in between, and Boulder is here to make sure you have the support you need.

Suboxone vs. other opioid use disorder medications

Three medications have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of opioid use disorder: buprenorphine, methadone, and naltrexone. All three have been shown to be effective and safe.

There isn’t one medication that’s right for everyone. “Each works differently, and the right choice depends on someone’s body, circumstances, and goals,” Dr. Pechter says.

We should have a solid understanding of Suboxone at this point, but for a quick recap:

  • Suboxone combines two medications to reduce withdrawal and cravings. It can help people feel steadier and better able to focus on their daily life.

Now let's take a closer look at the other two:

Methadone

Methadone is a long-acting opioid that also reduces withdrawal and cravings. It can be helpful for people who have used opioids heavily or for a long time.

How it's used:

  • Taken daily as a liquid or tablet
  • Provided in person at a licensed methadone clinic
  • Doses are closely monitored and adjusted

Methadone is often used if other medications haven't worked well or if a person would benefit from structured, daily support. “Methadone is effective, especially for people with severe opioid use disorder, but it’s tightly regulated,” Dr. Pechter explains. “Daily visits to a clinic, often for months, can make it hard to fit into real life, especially without reliable transportation. For some, the nearest methadone clinic would be hours away. “

Naltrexone

Naltrexone blocks opioids so that they don't have an effect if they are used. It does not help ease withdrawal and may not reduce cravings for everyone.

How it's used:

  • Taken as a daily pill or a monthly injection
  • Being completely free of opioids for 7 to 10 days before starting is recommended
  • Can be taken as a monthly injection

Dr. Pechter notes that needing to be entirely off opioids for 7 to 10 days can be a major barrier. "There’s also a higher overdose risk after stopping due to reduced opioid tolerance," she says.

All three medications can be helpful tools. What works best isn’t the same for everyone, and it can change as your goals, needs, and access to care change.

The bottom line

Suboxone can help reduce cravings and lower overdose risk, making everyday life easier to manage for many people. Because it’s flexible, it works well with real-world challenges like pharmacy delays, stress, or changes in use. Staying connected to care can help with safety and long-term stability. 

“Recovery isn’t one-size-fits-all. The goal isn’t to follow a script. We want to help you build a life that works for you. We’re here to support that, with evidence-based care, respect, and options that meet people where they are,” Dr. Pechter says.

If you're curious about whether Suboxone could be a good fit, Boulder is here to help. Call 888-422-6530 to speak with a care team member and learn more about getting started.

Frequently Asked Questions

Is Suboxone considered a narcotic?

Yes, Suboxone is considered a narcotic because it contains buprenorphine, which affects the same receptors as other opioids. But it's different from drugs like heroin, or oxycodone. Buprenorphine doesn’t turn on these receptors all the way, so it's safer and doesn't give the same rush or intense euphoria. It's still a controlled medication. It can help treat illness, but it still has risks if it’s used the wrong way.

What is the bad side of Suboxone?

Just like other medicines, Subox can have side effects. Some people get things like headaches, nausea, trouble sleeping, or constipation. Starting too soon can cause withdrawal, so working with your provider closely to get the time right is important. It needs to be taken as prescribed, so stopping too quickly can be uncomfortable. These side effects are manageable for most people, so the pros usually outweigh the cons.

Does insurance cover Suboxone?

Yes, many insurance plans cover Suboxone, but coverage varies by plan and policy. Some plans may require prior authorization or have limits on the amount covered. Boulder accepts many different health insurance plans, including Medicaid and Medicare. Out-of-pocket payments are also accepted in select states. Check to see if we take your insurance or explore our self-pay options.

What are opioid antagonists?

Opioid antagonists are medications that block the effects of opioids in the brain. They can prevent overdoses or reverse the effects of opioids. Some common examples include naloxone (the active ingredient in Narcan) and naltrexone.

How long do you stay on Suboxone?

There is no strict time limit for how long someone can stay on Suboxone. Some people use it for a few months, and others stay on it for a year or longer. Longer treatment can reduce the risk of overdose, hospitalizations, and opioid use.

What's the difference between Subutone and Subutex and these other medications?

While Suboxone contains naloxone, Subutex, Sublocade, and Brixadi only contain buprenorphine. Subutex was discontinued in the U.S., but buprenorphine is still widely used for opioid treatment as Suboxone, or in long-acting injections like Sublocade and Bixadi.

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